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Fluoxetine or Paroxetine with Codeine: Why Your Pain Relief Stops Working
Olly Steele 1 January 2026

Fluoxetine or Paroxetine with Codeine: Why Your Pain Relief Stops Working

Fluoxetine and paroxetine block the enzyme needed to turn codeine into morphine, making pain relief impossible. Learn why this interaction happens, what drugs to use instead, and how to avoid ineffective treatment.

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